Tissue Repair & Wound Healing
- Traumatic Lesions (burns)
- Dermal Ulcers
- Venous Stasis
- Compression
How does it help?
- Stimulates anti-inflammatory resolution
- Angiogenesis- The formation of new blood vessels
- Epithelial and fibroblast proliferation- helping to close over the wound with new skin cells
- Collagen synthesis and deposition
- Wound contraction
Effects of low-level laser therapy on wound healing- A Review
Andrade, F., Clark, R. and Ferreira, M. (2014). Effects of low-level laser therapy on wound healing. Revista do Colégio Brasileiro de Cirurgiões, 41(2), pp.129-133.
Abstract
Objective: To gather and clarify the actual effects of low-level laser therapy on wound healing and its most effective ways of application in human and veterinary medicine.
Methods: We searched original articles published in journals between the years 2000 and 2011, in Spanish, English, French and Portuguese languages, belonging to the following databases: Lilacs, Medline, PubMed and Bireme; Tey should contain the methodological description of the experimental design and parameters used.
Results: doses ranging from 3 to 6 J/cm2 appear to be more effective and doses 10 above J/cm2 are associated with deleterious effects. The wavelengths ranging from 632.8 to 1000 nm remain as those that provide more satisfactory results in the wound healing process.
Conclusion: Low-level laser can be safely applied to accelerate the resolution of cutaneous wounds, although this fact is closely related to the election of parameters such as dose, time of exposure and wavelength.
Kajagar, B., Godhi, A., Pandit, A. and Khatri, S. (2012). Efficacy of Low Level Laser Therapy on Wound Healing in Patients with Chronic Diabetic Foot Ulcers—A Randomised Control Trial. Indian Journal of Surgery, 74(5), pp.359-363.
Abstract
Foot ulcers are serious complications of Diabetes Mellitus (DM) and are known to be resistant to conventional treatment. They may herald severe complications if not treated wisely. Electromagnetic radiations in the form of photons are delivered to the ulcers in laser form to stimulate healing. This study was conducted to evaluate the efficacy of Low Level Laser Therapy (LLLT) in diabetic ulcer healing dynamics. To determine mean percentage reduction of wound area in study and control groups.
Settings: KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum.
Study Design: Randomized-Control Study.
Methods: A total of 68 patients with Type 2 DM having Meggitt-Wagner Grade I foot ulcers of atleast more than 4 weeks duration, less than 6×6 cm2 with negative culture were studied. Patients were randomized into two groups of 34 each. Patients in study group received LLLT with conventional therapy and those in control group were treated with conventional therapy alone. Healing or percentage reduction in ulcer area over a period of 15 days after com- mencement of treatment was recorded.
Statistical Analysis: Unpaired Student T Test and Mann Whitney U test. Mean age of the patients was 50.94 years in control group and 54.35 years in study group (p 0 0.065). There was no significant difference between control and study group with respect to mean FBS and HbA1c levels (p > 0.05), suggesting no biochemical differences between two groups. Initial ulcer area was 2608.03 mm2 in study group and 2747.17 mm2 in control group (p 0 0.361). Final ulcer area was 1564.79 mm2 in study group and 2424.75 mm2 in control group (p 0 0.361). Percentage ulcer area reduction was 40.24 ± 6.30 mm2 in study group and 11.87 ± 4.28 mm2 in control group (p < 0.001, Z 0 7.08). Low Level Laser Therapy is beneficial as an adjunct to conventional therapy in the treatment of diabetic foot ulcers (DFU).
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